tantalum for medical applications Artificial joints Specificity of the human environment

Human body fluids consist of about 1% sodium chloride and small amounts of other salts and organic compounds, with local acidity and alkalinity
Frequent slight changes, the temperature is maintained at about 37 ℃.
This environment produces corrosion of metallic materials, the corrosion products of which may be ions, oxides
chlorides, etc., which come into contact with neighbouring tissues or even penetrate into normal tissues or whole biological systems These products may be ions, oxides, chlorides, etc., which come into contact with neighbouring tissues or even penetrate into normal tissues or the entire biological system, affecting and stimulating normal tissues, causing abnormal growth, distortion allergy, inflammation, infection and other adverse biological reactions, and even induce cancer. Corrosive effects can cause the mechanical properties of materials to deteriorate. These two processes are usually responsible for the failure of the material, either individually or in concert.
Therefore, as a biomedical metal material, it must first meet two basic conditions: firstly, it is non-toxic; secondly, it is physiologically resistant.
Firstly, they are non-toxic; secondly, they are resistant to physiological corrosion.
Specificity of the human environment
Human body fluids consist of about 1% sodium chloride and small amounts of other salts and organic compounds, with local acidity and alkalinity
Frequent slight changes, the temperature is maintained at about 37 ℃.
This environment produces corrosion of metallic materials, the corrosion products of which may be ions, oxides
Chloride, etc., which are in contact with the neighbouring tissues, or even penetrate into the normal tissues or the whole biological system, affecting and stimulating the normal tissues, causing abnormal growth, distortion, allergy or inflammation, infection and other undesirable biological reactions, or even inducing cancerous changes. The mechanical properties of the material may be degraded by corrosion, and these two processes are usually responsible for the failure of the material, either alone or in combination.
Therefore, as a biomedical metal material, it must first meet two basic conditions: firstly, it is non-toxic; secondly, it is physiologically resistant.
The first is non-toxicity; the second is resistance to physiological corrosion.
Artificial joints implanted in the human body, generally want to be able to play a permanent or semi-permanent physiological function in the body, the so-called semi-permanent metal artificial joints at least in more than 15 years, in such a long time, the metal surface will be more or less ions or atoms due to corrosion or wear and tear into the surrounding biological tissues, so whether the material is toxic to biological tissues has become a necessary condition for the selection of materials.
Tantalum metal is basically non-reactive with human tissues, body fluids, blood and other components, and does not cause toxic and inflammatory reactions, and helps healing and fixation after implantation. Unlike traditional medical metal materials, biological tissue grows on Tantalum after a period of implantation, just as it grows on real bone. on real bone.